Vaccine precautions

Live vaccines are generally artificially weakened microorganisms, and may also be naturally weak microorganisms. The route of use is oral, injection, nasal drops, eye drops, aerosols, and the like. When used on the animal's body, it will multiply again and enlarge the quantity. If the body has specific antibodies or antibiotics, this amplification will be affected.

The live vaccine is obtained by cultivating the bacteria with good immunogenicity, culturing in an appropriate medium, inactivating the culture with formaldehyde, and adding an aluminum hydroxide gum solution to form an oil adjuvant; fully vibrating with sufficient shaking to maintain good emulsification , 20% aluminum hydroxide diluted saline, nasal drops or eye drops.

Inactivated vaccines are generally inactive microorganisms or microbial metabolic components containing adjuvants. Most of the way to use is injection. When the body is used, it does not proliferate and is not interfered by antibodies or antibiotics. Compared with viable vaccines, inactivated vaccines produce longer immune responses and longer immunization durations. After cell culture, the cells were frozen and vacuum dried, and injected intramuscularly or subcutaneously.

The problems that should be paid attention to during storage and transportation are generally protected from light at 2°C~8°C, with an effective period of one year; 16°C~28°C for nine months; oil-adjuvant inactivated vaccine cannot be frozen. You can make your own carrying case and put it in ice for storing and transporting the vaccine.

Problems that should be paid attention to in the use of vaccines (1) Whether the vaccine is applicable, attention should be paid to the prevalence of local diseases, and vaccines should be used during use; vaccines with strong virulence should be used with caution, otherwise they are harmful to young animals.

(2) Replace the needle promptly. When a livestock or poultry has a potential disease, using a continuous syringe can cause artificial infections. When injecting, it is necessary to clean the injection site and sterilize it with 75% alcohol to prevent the needle from bringing bacteria and viruses into the deep muscle tissue.

(3) Use joint seedlings as much as possible. In order to reduce the stress caused by vaccination on animals, it is common to use double and triple vaccines.

(4) Dosing method and operation. In the case of intramuscular injection, the vaccine acts on the deep part of the body, and oil solutions, suspensions, and emulsions are used. When subcutaneous injections, oil solutions, suspensions, and emulsions cannot be used to prevent necrosis of the surrounding tissues. Effects: Intravenous> Intramuscular> Hypodermic> Inhalation of gases, volatile drugs and aerosols> Drinking water.

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Obstetric Examination Table

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