Research on Dropping Technology of Dropping Pill Machine

The dropping method is the key technical means in the dropping process, and its influence on the weight of the pill is very obvious. At present, the dropping machine produced by more than ten domestic pill machine manufacturers generally adopts the natural dropping method and the pneumatic pulse. The drop method has the following advantages and disadvantages:

First, the natural drip method:

It is suitable for the drug with a moderate viscosity after melting of PEG. The weight of the drop is controlled mainly by the inner and outer diameter of the dripper. The weight of the Zui big pill is hard to exceed 70 mg. Due to the influence of the weight of the liquid, the difference in pill weight is obvious, and the pass rate is generally about 90%. If the constant pressure control of the drip tank is adopted, the pass rate of the pill can be further improved. Due to the difference in the physical properties of the liquid, the thickness of the liquid wall is different. Before determining the inner diameter and outer diameter of the dripper, it must be solved by the experimental machine. The disadvantages are as follows:
1. It is not suitable for liquid medicines that are too thick and too thin or have a small surface tension.
2, can not adjust the weight of the pill online, increase the 3mg will replace all the dripper.
3, Zui big drop system weight does not exceed 70mg.
4, the dropping pills loaded with less drug, the drug and PEG specific gravity is generally 1:3 ~ 1:4.

Second, the pressure pulse drop method:

In the past year, some manufacturers have adopted this method, which is suitable for dropping the liquid with high viscosity. The diameter of the dripper has little effect on the weight of the pellet. It can drip 50-400mg dropping pills and can be adjusted online. The drug loading of the dropping pills can be increased. The general drug and PEG can reach a specific gravity of 1:1. The disadvantages are as follows:
1. The difference in pill weight is large and the pass rate is low.
2, must be designed to prevent the dripper from blocking or leaking.
3. The gradient control of the cooling temperature is required to be high.
4, mainly suitable for experimental machines.

Zui near, the plunger type dripper developed by Bosen Pharmaceutical Machinery Co., Ltd. of Yantai Development Zone has fundamentally solved the problems of the above two kinds of dropping methods. The principle is: open the dripper switch to make the liquid medicine quantitatively under the action of air pressure. Enter the vertical plunger, after the switch is closed, the plunger will move down to force the liquid to be squeezed out. All the processes are automatically controlled. It is very convenient to adjust the weight of the pellet online by the scale micrometer. The drop weight can be 50-400mg. The error is about ±2%, and the drip speed can be adjusted arbitrarily. Online cleaning is also very convenient, and the dripper will never block. weakness is:
1. The precision of the dripper processing is high and the cost is increased.
2. Under certain conditions, the number of drippers is limited.
3. When dropping the pellets, the cooling gradient density that is complementary to them needs to be increased, which also increases the cost.

Yantai Bosen Pharmaceutical Machinery Co., Ltd. is a professional manufacturer of dropping pills machine. It is the unsatisfied pursuit and the serious and responsible attitude for users, so that we can dedicate high-tech products to users. We are determined to work together with you to modernize Chinese medicine. Make your own contribution.

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