Immunosuppressive Powder Tacrolimus CAS 104987-11-3 for Anti-Inflammatory

Model NO.: CAS: 104987-11-3
CAS: 104987-11-3
Mf: C44h69no12
MW: 804.02
Grade: Pharmaceutical Grade
Appearance: White to Light Yellow Crystal Powder
Transport: Discreet Package for Delivery Guarantee
Density: 1.19 g/cm3
Trademark: Nanjian
Transport Package: 1kg/Plastic Bottle or as Required
Specification: CAS: 104987-11-3
Origin: China
HS Code: 2937390000
Model NO.: CAS: 104987-11-3
CAS: 104987-11-3
Mf: C44h69no12
MW: 804.02
Grade: Pharmaceutical Grade
Appearance: White to Light Yellow Crystal Powder
Transport: Discreet Package for Delivery Guarantee
Density: 1.19 g/cm3
Trademark: Nanjian
Transport Package: 1kg/Plastic Bottle or as Required
Specification: CAS: 104987-11-3
Origin: China
HS Code: 2937390000
Thanks for you inqury, we show the product details for you.
 
There is an old saying in China: there are thousands of miles to meet, I believe that the next person I meet is you. Wish us a pleasant cooperation.Any need please feel free contact me.I am waiting for you coming.

Immunosuppressive Powder Tacrolimus CAS 104987-11-3 for Anti-inflammatory

Quick Detaiils of Tacrolimus:
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Synonyms: (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide
Grade: Pharmaceutical Grade
Appearance: White to Light Yellow Crystal Powder
Transport: Discreet Package for Delivery Guarantee
Density: 1.19 g/cm3

Tacrolimus Descriptions:
Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is animmunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

Tacrolimus Applications:
The mechanism of action of tacrolimus in atopic dermatitis is not known. While the following have been observed, the clinical significance of these observations in atopic dermatitis is not known. It has been demonstrated that tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12.
 
A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited. This prevents the dephosphorylation and translocation of nuclear factor of activated T-cells (NF-AT), a nuclear component thought to initiate gene transcription for the formation of lymphokines.
 
Tacrolimus also inhibits the transcription for genes which encode IL-3, IL-4, IL-5, GM-CSF, and TNF-, all of which are involved in the early stages of T-cell activation. Additionally, tacrolimus has been shown to inhibit the release of pre-formed mediators from skin mast cells and basophils, and to downregulate the expression of FceRI on Langerhans cells.
 
Usages:
Tacroz Forte Ointment (Tacrolimus) is used to treat atopic dermatitis (more commonly known as eczema). It is a topical medication which is normally prescribed for patients who have not responded successfully to other eczema medication.
 
The ointment is a type of topical calcineurin inhibitor (TCIs) that works by weakening the patient`s immune system, which as a consequence directly reduces the severity of eczema and its symptoms. It should not be used by patients who have any kind of weak immune system.

Immunosuppressive Powder Tacrolimus CAS 104987-11-3 for Anti-Inflammatory


Our order process:
1st: Please let us know the products you are interested in via email,
2nd:You confirm all details of the order,such as:price,packing,express company,shipping method etc...
3rd:About payment,we can accept:T/T,Western Union,Money Gram.
4th:Goods sent within 24 hours after payment received,Photo of the parcel and tracking number can be offered timely.
5th:24/7 online after-sale service after you receive your parcel.

Our advantages:
1,Quality products with factory price;
2,We are manufacturer,products plenty in stock and orders can be delivered in the first time;
3,Rich experienced packing and delivery department,packages well disguised,fast and safe delivery,pass rate above 99%;
4,Express company:EMS,HKEMS,Fedex,TNT,UPS,DHL etc;
5,We have reship policy if parcel can't reach your hands due to custom;
6,24/7 online after-sales service.

Dear Friend,
 
As I know the product description won't satisfy all your questions.
Contact me.I'll reply the fastest.


  Thanks for you inqury, we show the product details for you.
 
There is an old saying in China: there are thousands of miles to meet, I believe that the next person I meet is you. Wish us a pleasant cooperation.Any need please feel free contact me.I am waiting for you coming.

Immunosuppressive Powder Tacrolimus CAS 104987-11-3 for Anti-inflammatory

Quick Detaiils of Tacrolimus:
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Synonyms: (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide
Grade: Pharmaceutical Grade
Appearance: White to Light Yellow Crystal Powder
Transport: Discreet Package for Delivery Guarantee
Density: 1.19 g/cm3

Tacrolimus Descriptions:
Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is animmunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

Tacrolimus Applications:
The mechanism of action of tacrolimus in atopic dermatitis is not known. While the following have been observed, the clinical significance of these observations in atopic dermatitis is not known. It has been demonstrated that tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12.
 
A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited. This prevents the dephosphorylation and translocation of nuclear factor of activated T-cells (NF-AT), a nuclear component thought to initiate gene transcription for the formation of lymphokines.
 
Tacrolimus also inhibits the transcription for genes which encode IL-3, IL-4, IL-5, GM-CSF, and TNF-, all of which are involved in the early stages of T-cell activation. Additionally, tacrolimus has been shown to inhibit the release of pre-formed mediators from skin mast cells and basophils, and to downregulate the expression of FceRI on Langerhans cells.
 
Usages:
Tacroz Forte Ointment (Tacrolimus) is used to treat atopic dermatitis (more commonly known as eczema). It is a topical medication which is normally prescribed for patients who have not responded successfully to other eczema medication.
 
The ointment is a type of topical calcineurin inhibitor (TCIs) that works by weakening the patient`s immune system, which as a consequence directly reduces the severity of eczema and its symptoms. It should not be used by patients who have any kind of weak immune system.

Immunosuppressive Powder Tacrolimus CAS 104987-11-3 for Anti-Inflammatory


Our order process:
1st: Please let us know the products you are interested in via email,
2nd:You confirm all details of the order,such as:price,packing,express company,shipping method etc...
3rd:About payment,we can accept:T/T,Western Union,Money Gram.
4th:Goods sent within 24 hours after payment received,Photo of the parcel and tracking number can be offered timely.
5th:24/7 online after-sale service after you receive your parcel.

Our advantages:
1,Quality products with factory price;
2,We are manufacturer,products plenty in stock and orders can be delivered in the first time;
3,Rich experienced packing and delivery department,packages well disguised,fast and safe delivery,pass rate above 99%;
4,Express company:EMS,HKEMS,Fedex,TNT,UPS,DHL etc;
5,We have reship policy if parcel can't reach your hands due to custom;
6,24/7 online after-sales service.

Dear Friend,
 
As I know the product description won't satisfy all your questions.
Contact me.I'll reply the fastest.


 

October 24, 2018