Model NO.: 864070-44-0
Name: Empagliflozin
CAS: 864070-44-0
Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk
Sample: Free
Trademark: zsyh
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 134657687
Model NO.: 864070-44-0
Name: Empagliflozin
CAS: 864070-44-0
Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk
Sample: Free
Trademark: zsyh
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 134657687
Quack Detail for EMpagliflozinÂ
| Product Name: |
EMpagliflozin |
| Synonyms: |
EMpagliflozin;BI-10773;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol;EMpagliflozin/ BI-10773;EMPAGLIFLBZIN;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxyMethyl)-tetrahydro-2H-pyran-3,4,5-triol;D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]M ethyl]phenyl]-, (1S)-;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Empagliflozin BI 10773 |
| CAS: |
864070-44-0 |
| MF: |
C23H27ClO7 |
| MW: |
450.90928 |
| Product Categories: |
API;Inhibitors |
| Mol File: |
864070-44-0.mol |
| Usage |
Empagliflozin is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. |
Empagliflozin is an inhibitor with the sodium glucose co-transporter-2 (SGLT-2), and results in sugar in the blood being excreted by the kidneys and eliminated in urine.
About the Empagliflozin
Empagliflozin is really a selective inhibitor of SGLT-2 with IC50 value of 3.1 nM .
Sodium glucose cotransporter-2 (SGLT-2) is part of sodium glucose co-transporter family and plays a pivotal role in glucose reabsorption in the kidney .
Empagliflozin is a potent SGLT-2 inhibitor and it has a high amount of selectivity over SGLT-1, 4, 5 and 6 than other reported SGLT-2 inhibitors. When tested using a panel of human cell lines over-expressed SGLT-1, 2, 4, 5 and 6,
Empagliflozin treatment competitively bind to SGLT-2 over glucose at low dose . In human proximal tublular cell (PTC) cell line HK2 cells, Empagliflozin answer to 72 h inhibits the expression of SGLT-2 which reversed high glucose induced TLR4 expression, NF-κB binding, IL-6 secretion, AP-1 binding and CIV expression .
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Our AdvantageÂ
| Best Quality |
Professional leading manufacturers in China.Strict
quality control before products are allowed to sell. |
| Competitive Price |
Factory direct sales.Best prices you're sure to be
satisfied. |
| Safe Packing |
Professional packing department which have more
than 16 years experience in disguising packages |
| Fast Delivery |
Plenty in stock,delivery within 24 hours after the
payment.Fast and secure delivery by DHL, TNT,
FedEx, HKEMS, UPS, etc. |
| Payment |
T/T,Western Union,Money Gram,Bitcoin. |
| Service |
Photos of parcel and tracking number offered
timely;24/7 online helpful service |
| Discount |
Specials are possible when client's order is big
enough, including the discount policy |
Â
Quack Detail for EMpagliflozinÂ
| Product Name: |
EMpagliflozin |
| Synonyms: |
EMpagliflozin;BI-10773;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol;EMpagliflozin/ BI-10773;EMPAGLIFLBZIN;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxyMethyl)-tetrahydro-2H-pyran-3,4,5-triol;D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]M ethyl]phenyl]-, (1S)-;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Empagliflozin BI 10773 |
| CAS: |
864070-44-0 |
| MF: |
C23H27ClO7 |
| MW: |
450.90928 |
| Product Categories: |
API;Inhibitors |
| Mol File: |
864070-44-0.mol |
| Usage |
Empagliflozin is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats. |
Empagliflozin is an inhibitor with the sodium glucose co-transporter-2 (SGLT-2), and results in sugar in the blood being excreted by the kidneys and eliminated in urine.
About the Empagliflozin
Empagliflozin is really a selective inhibitor of SGLT-2 with IC50 value of 3.1 nM .
Sodium glucose cotransporter-2 (SGLT-2) is part of sodium glucose co-transporter family and plays a pivotal role in glucose reabsorption in the kidney .
Empagliflozin is a potent SGLT-2 inhibitor and it has a high amount of selectivity over SGLT-1, 4, 5 and 6 than other reported SGLT-2 inhibitors. When tested using a panel of human cell lines over-expressed SGLT-1, 2, 4, 5 and 6,
Empagliflozin treatment competitively bind to SGLT-2 over glucose at low dose . In human proximal tublular cell (PTC) cell line HK2 cells, Empagliflozin answer to 72 h inhibits the expression of SGLT-2 which reversed high glucose induced TLR4 expression, NF-κB binding, IL-6 secretion, AP-1 binding and CIV expression .
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CAS 79559-97-0 |
| Piracetam    |
CASÂ Â 7491-74-9 |
| Tianeptine Sodium |
CASÂ Â 30123-17-2 |
| Paroxetine hydrochloride |
CAS 78246-49-8 |
| Adrafinils |
 CAS 63547-13-7 |
| Phenibut |
CAS 1078-21-3 |
| Trazodone HCl |
CAS 25332-39-2 |
| Venlafaxine HCl   |
CAS 99300-78-4 |
| Duloxetine HCl |
CAS 136434-34-9 |
| Mirtazapine(Remeron) |
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| Vortioxetine |
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| Doxepin HCL |
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| Duloxetine |
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| Tandospirone |
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| Tianeptine Sulphate |
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Our AdvantageÂ
| Best Quality |
Professional leading manufacturers in China.Strict
quality control before products are allowed to sell. |
| Competitive Price |
Factory direct sales.Best prices you're sure to be
satisfied. |
| Safe Packing |
Professional packing department which have more
than 16 years experience in disguising packages |
| Fast Delivery |
Plenty in stock,delivery within 24 hours after the
payment.Fast and secure delivery by DHL, TNT,
FedEx, HKEMS, UPS, etc. |
| Payment |
T/T,Western Union,Money Gram,Bitcoin. |
| Service |
Photos of parcel and tracking number offered
timely;24/7 online helpful service |
| Discount |
Specials are possible when client's order is big
enough, including the discount policy |
Â