American scientists have recently cultivated a genetically modified potato that can act as a hepatitis B vaccine. This result may help developing countries in the prevention and treatment of hepatitis B. Hepatitis B virus attacks the liver and kills about 500,000 people each year in the world. However, the traditional Hepatitis B vaccine needs to be refrigerated, which is difficult to achieve in the remote areas of developing countries. In addition, medical personnel often need to spend energy to determine whether the expensive Hepatitis B vaccine has failed due to accidental heat during transportation. Charles Arnchen, a biologist at the University of Arizona in the United States, and his colleagues have developed a solution that eliminates the need for refrigerated, edible hepatitis B vaccine potatoes. They took a gene from the hepatitis B virus and transplanted it into a potato plant to produce a virus antigen in the potato. After people eat this kind of potato, the antigen protein will trigger the body's immune response and produce hepatitis B antibody against the hepatitis B virus. In clinical trials, participants participated in the initial vaccination of hepatitis B vaccine in the past 1 to 15 years. The results showed that 19 out of 33 people had more hepatitis B antibodies after eating potatoes, and one of them had a 56-fold increase in antibody levels. Arneng et al. reported their test results in a new issue of the "Journal of the National Academy of Sciences". According to the researchers, potato vaccines work in nearly 60% of the test subjects and the effect is quite satisfactory. Julian Mare, an immunologist at the St. George's Hospital Medical School in London, United Kingdom, said that although this genetically modified potato is not yet a substitute for the initial vaccination of the hepatitis B vaccine, it can replace multiple repeated injections used to maintain immunity in the later stages. Health has a major impact."
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